031 Inducible skin-associated lymphoid tissue (iSALT) is detected in the scalp treated with topical immunotherapy for alopecia areata
نویسندگان
چکیده
منابع مشابه
Dapsone versus topical immunotherapy in alopecia areata.
Twenty-seven patients with severe alopecia areata were treated with dapsone. The results of a mean treatment duration of 10 +/- 0.5 months are reported, and compared with the results of long-term topical immunotherapy obtained previously at the same institute. The efficacy of dapsone proved to be markedly inferior to that of topical immunotherapy. The percentage of patients showing regrowth of ...
متن کاملNovel concept of iSALT (inducible skin-associated lymphoid tissue) in the elicitation of allergic contact dermatitis
Allergic contact dermatitis (ACD) is one of the most common inflammatory skin diseases, which is classified as a delayed-type hypersensitivity immune response. The development of ACD is divided into two phases: sensitization and elicitation. In the sensitization phase, antigen-specific effector T cells are induced in the draining lymph nodes by antigen-captured cutaneous dendritic cells (DCs) t...
متن کاملNovel insights into the role of immune cells in skin and inducible skin-associated lymphoid tissue (iSALT)
The skin is equipped with serial barriers that provide rapid and efficient protection against external intruders. Beneath the epidermal physical barriers of the stratum corneum and the tight junctions, the integrated immune systems in both the epidermis and the dermis act in a coordinated manner to protect the host. This "immunological" barrier is composed of various cells, including skin-resid...
متن کاملEfficacy of topical immunotherapy of extensive and/or chronic Alopecia Areata with Diphencyprone
Background: Highly variable results of topical immunotherapy with Diphencyprone (DPC) in the treatment of Alopecia areata have been reported so far. Objective: The purpose of this study was to evaluate the efficacy and tolerability of DPC in the treatment of severe and chronic chronic Alopecia areata. Patients and Methods: 28 patients (16 female and 12 male, 10-35 years old, mean age 25 years) ...
متن کاملTopical Immunotherapy of Alopecia Areata: A Large Retrospective Study
INTRODUCTION Topical immunotherapy is frequently used in the treatment of alopecia areata (AA) although few studies report long-term follow-up. Our goals were to determine the efficacy and the prognostic factors of topical immunotherapy in a large cohort of patients with AA treated in the departments of Dermatology and Venereology of Bergamo, Como and Pavia, from 1978 to January 2016. METHODS...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2017
ISSN: 0022-202X
DOI: 10.1016/j.jid.2017.02.044